This is Infertility is a bi-weekly podcast where we fuse narrative storytelling with experience and science to give you a new perspective on what it’s really like to go through a family building journey. Each episode dives into the emotional, physical, and financial burdens carried by those who experience infertility on their path to parenthood. Be it IVF, IUI, egg freezing, surrogacy, adoption, etc., the path is never the same and it can be long, painful, and lonely. It’s our mission to give those struggling a platform to be heard, a community connection, and an opportunity to raise awareness of the 1 in 6 who, for many reasons, struggle with infertility.
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This is Infertility

Episode 165: Fertility 101: Menopause

The Fertility 101 Series, because there’s no shortage of daunting terms to keep your mind running, is a quick and dirty breakdown on a specific topic with insights from a fertility expert.

In today’s episode, Progyny’s Chief Medical Officer and Reproductive Endocrinologist, Dr. Janet Choi gives an overview about all the things you need to know about menopause.

Menopause has long been an undiscussed and overlooked medical issue despite the fact that it will impact half of the population after the age of 50. While the scope of care for those going through menopause is not yet where it needs to be, becoming well-versed in the concept is the first step to caring for yourself or others in this transitional stage of life. Dr. Choi breaks down the classic symptoms and mental health effects surrounding menopause, as well as how one might mitigate these bodily changes with treatments. She also touches on her own experience and outlines life with menopause, next steps, and why menopause should be better supported.

Guest: Dr. Janet Choi, Chief Medical Officer at Progyny

Host: Dan Bulger, Progyny

For more information, visit Progyny’s Podcast page and Progyny’s Education page for more resources. Be sure to follow us on Instagram, @ThisisInfertilityPodcast and use the #ThisisInfertility. Have a question, comment, or want to share your story? Email us at

This podcast is also available on YouTube if you’d prefer to watch the podcast in video format:

Here are some highlights from this episode:

Why now? And for Who?

03:31 – 05:40

Dr. Janet Choi: There was a Mayo Clinic study that came out this spring that got a lot of press, showing that 40% of the workforce are comprised of women in their menopausal years. 45 to 54 is sort of the peak era of timelines when these issues crop up. That’s a pretty significant chunk of your workforce that really needs to be well supported, if you want to retain them. The average age of menopause is around 51 years of age. Less than 1% of women will experience menopause under the age of 40. About 5% of women will experience early menopause when this happens in their early 40s, before the age of 45. But again, if you make it into your 50s and beyond, everyone is going to experience menopause. Females are born with a set number of eggs, one to two million preformed eggs hunkered in their little follicle cells in the ovaries. As we age, the egg count disappears and goes down, the quantity goes down, the quality goes down. At a certain point in time, the egg count is so low or as close to zero, that your ovaries just stopped secreting this very important hormone called estrogen, which then leads to an absent slew of periods.


06:16 – 09:08

Dr. Janet Choi: Women in the pre-menopausal period, and this average age starts around age 47, will have regular or irregular periods. Period links become more unpredictable and start to have symptoms like hot flushes like headaches, like vaginal dryness, like mood disturbances, more depression or anxiety, all of those things kind of go part and parcel as your hormones start to change. But again, the most common complaint women in the peri-menopausal transition menopausal years will report back are hot flashes. Another really important thing just to be aware of as your estrogen levels drop, your bone health also declines. And this is something that’s really important to pay attention to because osteoporosis is one of the most common causes of morbidity later on in life for women. Up until menopause, women also have a healthier cardiovascular profile in general compared to their male counterparts. But as the estrogen levels drop, the cardiovascular risks like having a heart attack having changes in your lipid, your cholesterol, LDL starts to creep up for a lot of women. So, heart disease risks start to go up as well.

Treatment Options

09:31 – 12:50

Dr. Janet Choi: If you don’t want to resort to medical therapy straightaway. Some things may actually help with hot flash management if that’s really interfering with your daily living and your sleep habits. Trying to make sure you keep a cool dark room, and temperature-regulate through how you dress. There have been some limited studies looking at dietary management of hot flashes like trying to avoid things like alcohol and spicy foods. Although those have not been well proven to be that impactful, it doesn’t hurt to try. If you are in the obesity category, so body mass index of 30 or higher, there actually have been some good studies showing that weight loss may help lower the rate of hot flashes. When it comes to medical therapy – there’s FDA approved medication out there — hormone therapy that’s in different shapes and forms. It’s not just an estrogen pill, it’s not just Premarin. We also have Estradiol pills, or sticker patches that you could put on once or twice a week. Or for people who don’t want that much systemic estrogen, if your main complaint is vaginal dryness, a little estrogen pill put into the vagina to help with a local lubrication. Those are all remedies.

Now, if you have a uterus, you need to be able to balance out the estrogen impact with progesterone because you don’t want to increase your risk for uterine cancer, that’s controllable by making sure that you and your doctor discuss the scheduled cyclic or continuous use of progesterone. Now, if you don’t have a uterus, this is where you can celebrate, you don’t need the progesterone. There is also now an FDA approved drug that came out this spring or summer called Veozah. It seems to be very effective. And it’s a non-hormonal solution to manage moderate to severe hot flashes., If you don’t want to use estrogen or if your doctor deems estrogen potentially a little risky for you based on your medical profile. If you are having lots of mood disorders, if you’re finding that your depression or anxiety is flaring up with a pre-menopausal transition and you’re having hot flashes — you and your doctor might decide that instead of trying hormone therapy, you might want to try an antidepressant. It’s not just estrogen therapy in the end.

To Keep in Mind

19:47 – 26:36

Dr. Janet Choi: Although there are women who are able to conceive healthy pregnancies and babies into their mid-40s, sometimes without any medical assistance. Because those eggs are older in quality. The ability of these eggs to create genetically healthy pregnancies is much, much lower than when you use eggs from, say, someone who’s even 40 or 35. The benefit of IVF is if your doctor is able to extract eggs, and with their lab team create embryos, they can screen those embryos through PGT-A, Pre Implantation Genetic Testing for Aneuploidy, to let you know before you conceive and use those embryos if there are any embryos that are actually chromosomally normal or euploid, before you go through the embryo transfer process.

It’s also important to stay abreast of your specialist appointments too in terms of health, maintenance, mammograms. It’s really important to stay on top of that, whether it’s once a year, every two years, depending on your doctors’ guidelines and also recommendations. Colonoscopy — colon cancer risks go up as we get older. And you want to just make sure that you’re doing the proper screening of your colon with your proper physician.

It’s the stigma against aging, which shouldn’t be there. And the stigma against having these symptoms, which are, you know, they don’t seem like life threatening, but it is something that most women have to live with. And it should be well supported.

Dan Bulger


Dan Bulger
Producer at Progyny

Dan has been in the healthcare industry for the past ten plus years as a multimedia content producer. Better known as ‘Video Dan’ he has interviewed numerous doctors, patients and other experts in the world of fertility. He’s also the producer for this podcast, This is Infertility and the producer behind the Progyny YouTube Channel which features interviews with dozens of the nation’s leading fertility specialists. On a personal note Dan’s parents started fostering kids when he was four years old, and he considers himself a proud older brother to over 100 foster children.

Dr. Janet Choi


Dr. Janet Choi
Chief Medical Officer at Progyny

Dr. Janet Choi is a highly ranked board-certified REI, bringing over two decades of clinical expertise in fertility and family building. Dr. Choi has published and lectured extensively on infertility, onco-fertility, and fertility preservation. She is a member of ASRM, ACOG, and the NY Obstetrical Society. She earned her medical degree and completed her residency at Columbia University and completed her REI fellowship at Weill Cornell Medical College.

Music From This Episode:

Artist: Doctor Turtle
Track: The Ants Built a City on His Chest

Track: Where I lay my hat that’s my wife

Artist: Steve Combs
Track: Small Spaces

Artist: Jahzzar
Track: Sleepin’
Track: Dew
Track: MainSquare